Saffron contains an impressive variety of plant compounds that act as antioxidants — molecules that protect your cells against free radicals and oxidative stress.   taking 30 mg of saffron daily was just as effective as Fluoxetine, Imipramine, and Citalopram — conventional treatments for depression. Additionally, fewer people experienced side effects from saffron compared to other treatments Saffron is high in antioxidants, which help neutralize harmful free radicals. Free radical damage has been linked to chronic diseases, such as cancer Premenstrual syndrome (PMS) is a term that describes physical, emotional, and psychological symptoms occurring before the start of a menstrual period. Studies show that saffron may help treat PMS symptoms. In women 20–45 years of age, taking 30 mg of saffron daily was more effective than a placebo at treating PMS symptoms, such as irritability, headaches, cravings, and pain